Nasal spray for a younger brain

Innovative Marche discovery promises to slow brain ageing

An Italian research conducted by a team of scientists from INRCA and the Università Politecnica delle Marche has opened new perspectives in the fight against brain aging. Researchers have found that a simple nasal spray may be able to rejuvenate brain cells, improving memory and cognitive abilities.

The secret? Extracellular vesicles

The focus of the study is on the so-called extracellular vesicles, tiny bubbles produced by our body’s cells. These vesicles contain molecules that serve to communicate between cells and regulate different functions.
Researchers have found that vesicles produced by a particular type of brain cell, called microglia, have a powerful anti-inflammatory effect. By administering these vesicles through the nose to elderly mice, scientists have observed a real rejuvenation of brain cells, with a reduction in inflammation and an improvement in cognitive functions.

Surprising results

The results of the study were surprising: mice treated with nasal spray showed increased learning and memory, as well as reduced anxiety. In addition, the researchers observed interesting differences between males and females, suggesting that brain ageing may have different mechanisms in the two sexes.

A promising future

This discovery opens the way to new and promising therapies for combating neurodegenerative diseases. A simple nasal spray could become an effective tool for preventing and treating these diseases, improving the quality of life of millions of people around the world.

An important discovery

The rector of the Università Politecnica delle Marche, Gian Luca Gregori, expressed great satisfaction with the results obtained by the research group, stressing the importance of this discovery for the international scientific community.

A significant milestone

This research represents a significant step forward in understanding the mechanisms of brain ageing and opens new perspectives for the development of innovative therapies. Although further studies are needed to confirm these findings in humans, this discovery offers real hope for the future of our brain health.

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