Acebutolol: what it is used for and what side effects it has
Acebutolol is an antihypertensive beta-receptor blocker (also called ‘beta-adrenergic blocker’ or simply ‘beta-blocker’)
The function of beta-blockers is to inhibit the beta receptors of the adrenergic system in the heart, reducing cardiac effort
It is classified as a cardioselective drug (i.e. it acts mainly on the heart more than on other tissues) and also has intrinsic sympathomimetic activity (i.e. it is able to modulate its action by inhibiting the nervous system’s response to stimuli from adreanline and other catecholamines, while also providing mild stimulation) and membrane-stabilising properties (it acts on the cell membrane by preventing the opening of ion channels and the modification of cellular electrical potential).
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What is Acebutolol used for?
Acebutolol is used in cardiology against pathological conditions such as:
It is also used for protective purposes in patients who have suffered an acute myocardial infarction.
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How is Acebutolol taken?
Acebutolol is commercially available as tablets for oral use and as a solution for injections.
Side effects of Acebutolol
Recognised side effects include:
- headache
- dyspnoea
- psychosis
- dizziness
- nausea
- drowsiness
- sexual dysfunction
- bradycardia
- alopecia
- xerophthalmia
- fatigue
- purpura
- heart failure
- hypotension
- rash
- bronchospasm
- irritation.
Contraindications and warnings associated with the use of Acebutolol
Acebutolol is not recommended for use in people who suffer or have suffered from asthma and bronchospasm and heart failure.
Particular attention should be paid to diabetics. Acebutolol should not be used during pregnancy or when breast-feeding.
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