Streptococcal infections: the antistreptolysin titre (TAS or ASLO)
The Antistreptolysin titre (TAS) is the rate of antibodies produced in response to contact with streptococcus
What the Antistreptolysin titre (TAS) is used for
This is the serological test used for the diagnosis of infection – current or previous – caused by beta-haemolytic streptococcus type A. It becomes positive approximately one week after contact.
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Antistreptolysin titre (TAS) values
The TAS becomes positive one week after infection, with a progression that peaks after 3-5 weeks; it then decreases over the following months.
A moderate increase may indicate an infection of the first airways (rhinitis, tonsillitis, pharyngitis), scarlet fever or erythema nodosum.
A substantial increase may indicate acute joint rheumatism or glomerulonephritis.
False positives may occur in cases of cholestasis, pulmonary tuberculosis and hypercholesterolaemia.
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