The Lethal Trauma Triad: A Guide for Emergency Workers

Hypothermia, coagulopathy and acidosis: a major cause of death in traumatized patients

The lethal triad of trauma is a lethal combination of three medical conditions – hypothermia, coagulopathy and acidosis – which often develop in chain reaction in severely traumatised patients. This syndrome is one of the main preventable causes of death in traumatised patients, making a rapid and effective intervention by emergency workers essential.

What it is and how it develops

  • Hypothermia: Lowering of body temperature below 35°C. Hypothermia impairs coagulation, alters cellular metabolism and contributes to acidosis
  • Coagulopathy: Alteration of blood coagulation, which can lead to internal and external hemorrhages. Hypothermia exacerbates coagulopathy
  • Acidosis: Increased blood acidity. Acidosis is often caused by shock, organ failure and blood loss

The vicious circle of death

These three conditions create a vicious circle: hypothermia worsens coagulopathy, which in turn causes increased blood loss and therefore more severe acidosis. Acidosis, finally, aggravates hypothermia, completing the cycle.

Emergency response: preventing and treating

The intervention of emergency workers is crucial to break this vicious circle and improve the patient’s prognosis.

  • Prevention:
    • Maintaining body temperature: Use thermal blankets, heat the infused fluids and protect the patient from further heat loss
    • Bleeding control: Apply effective compression to wounds, administer local hemostats and prepare the patient for rapid transfusion
    • Continuous monitoring: Frequently assess body temperature, vital signs and signs of coagulopathy
  • Treatment:
    • Active heating: Use heating devices to raise body temperature in a controlled manner
    • Electrolyte corrections: Administer crystalloid and colloid solutions to restore blood volume and correct electrolyte imbalances
    • Respiratory support: Ensure adequate oxygenation and ventilation
    • Transfusions: Administer blood products (red blood cells, fresh frozen plasma) to correct anemia and coagulative deficits
    • Drug therapy: Administer vasoconstrictor drugs, coagulation drugs and bicarbonate (with caution)

A multidisciplinary approach

The management of the lethal triad requires a multidisciplinary approach and close collaboration between all health care professionals involved. Rapid, effective and scientifically-based intervention can make the difference between life and death for a traumatised patient.

Sources and images

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