The annual observance of the International Day of Disabled Persons was proclaimed in 1992, by the United Nations General Assembly resolution 47/3. The observance of the Day aims to promote an understanding of disability issues and mobilize support for the dignity, rights and well-being of persons with disabilities. It also seeks to increase awareness of gains to be derived from the integration of persons with disabilities in every aspect of political, social, economic and cultural life. 

Since 2009, the Department of Economic and Social Affairs organizes a film festival as a part of the events at UN Headquarters to commemorate the Day. The United Nations Enable Film Festival (UNEFF) includes short disabilty-related films selected on the basis of their content and message that can help raise awareness of disability issues and further promote the full and effective participation of persons with disabilities in society.

Since 2015, the Department of Economic and Social Affair organizes a Photo Exhibition. The UN Enable Photo Exhibition will work to help change misperceptions to counter stigma and stereotyping about persons with disabilities. It will also promote a better understanding about disability issues and present persons with disabilities as individuals that are a part of our human diversity.